Amrinone stimulation test: Ability to predict improvement in left ventricular ejection fraction after coronary bypass surgery in patients with poor baseline left ventricular function
| Autor: | Eduardo Mele, Alfredo E. Rodriguez, Nestor Perez-Baliño, Osvaldo Masoli, Sergio V. Perrone, Igor F. Palacios, Fernando Boullon, Daniel Cragnolino, Alejandro Meretta, Kenneth A. Brown |
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| Rok vydání: | 1996 |
| Předmět: |
Male
medicine.medical_specialty Cardiotonic Agents animal structures Ischemia Coronary Disease Amrinone Coronary artery disease Internal medicine Humans Medicine Coronary Artery Bypass Aged Aged 80 and over Hibernating myocardium Ejection fraction business.industry Hemodynamics Stroke Volume Middle Aged medicine.disease medicine.anatomical_structure Bypass surgery Anesthesia Cardiology Female Dobutamine medicine.symptom Cardiology and Cardiovascular Medicine business medicine.drug Artery |
| Zdroj: | Journal of the American College of Cardiology. 28:1488-1492 |
| ISSN: | 0735-1097 |
| Popis: | Objectives. This study sought to determine whether the response to amrinone in patients with severe baseline left ventricular dysfunction can predict improvement in left ventricular ejection fraction after coronary artery bypass graft surgery.Background. Previous studies have suggested that the inotropic response to dobutamine can identify viable myocardium in the setting of chronic coronary disease and left ventricular dysfunction. However, increased oxygen demand stimulated by dobutamine can lead to superimposition of ischemia on the hibernating state, potentially confounding interpretation of results. Amrinone is an inotropic agent that does not critically augment myocardial oxygen demand and may be useful for identification of hibernating myocardium in the chronically ischemic state.Methods. Forty-four consecutive patients with coronary artery disease and left ventricular ejection fraction |
| Databáze: | OpenAIRE |
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