A toolbox of Cre-dependent optogenetic transgenic mice for light-induced activation and silencing
| Autor: | Xuan Gu, Edward S. Boyden, Hong Gu, Jia-Min Zhuo, Xue Han, Sebastien Zanella, Jolene Kidney, György Buzsáki, Karel Svoboda, Alfredo J. Garcia, Antal Berényi, Jan-Marino Ramirez, Shigeyoshi Fujisawa, Bryan M. Hooks, Eric E. Turner, Allan R. Jones, Henner Koch, Hongkui Zeng, Linda Madisen, Yimei Mao, Tianyi Mao, Yun Wei A Hsu |
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| Přispěvatelé: | CMBN, Rutgers, The State University of New Jersey [New Brunswick] (RU), Rutgers University System (Rutgers)-Rutgers University System (Rutgers), Centre de recherche en neurobiologie - neurophysiologie de Marseille (CRN2M), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Genes and Development Research Group - Department of Biochemistry and Molecular Biology and Department of Medical Genetics, University of Calgary, University of Calgary, Department of Neuroscience, Physiology and Pharmacology, Massachusetts Institute of Technology. Media Laboratory, Boyden, Edward |
| Jazyk: | angličtina |
| Rok vydání: | 2012 |
| Předmět: |
Genetically modified mouse
Optics and Photonics RNA Untranslated Light Transgene Archaeal Proteins Neurogenesis Channelrhodopsin Action Potentials Mice Transgenic Biology Optogenetics In Vitro Techniques Article 03 medical and health sciences Mice 0302 clinical medicine Channelrhodopsins Premovement neuronal activity Gene silencing Animals Wakefulness [SDV.BBM.BC]Life Sciences [q-bio]/Biochemistry Molecular Biology/Biochemistry [q-bio.BM] 030304 developmental biology Neurons 0303 health sciences Integrases General Neuroscience fungi Brain Proteins 3. Good health Halorhodopsin Luminescent Proteins Electroporation nervous system Halorhodopsins Neuroscience 030217 neurology & neurosurgery |
| Zdroj: | Nature Neuroscience Nature Neuroscience, Nature Publishing Group, 2012, 15 (5), pp.793-802. ⟨10.1038/nn.3078⟩ Nature Neuroscience, 2012, 15 (5), pp.793-802. ⟨10.1038/nn.3078⟩ Nature neuroscience PMC |
| ISSN: | 1097-6256 1546-1726 |
| Popis: | We report on wide-field optically detected magnetic resonance imaging of nitrogen-vacancy centers (NVs) in type IIa polycrystalline diamond. These studies reveal a heterogeneous crystalline environment that produces a varied density of NV centers, including preferential orientation within some individual crystal grains, but preserves long spin coherence times. Using the native NVs as nanoscale sensors, we introduce a three-dimensional strain imaging technique with high sensitivity ( Allen Institute for Brain Science Howard Hughes Medical Institute |
| Databáze: | OpenAIRE |
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