Epidemiological and microbiological investigation of a large increase in vibriosis, northern Europe, 2018
| Autor: | Ettore Amato, Maximilian Riess, Daniel Thomas-Lopez, Marius Linkevicius, Tarja Pitkänen, Tomasz Wołkowicz, Jelena Rjabinina, Cecilia Jernberg, Marika Hjertqvist, Emily MacDonald, Jeevan Karloss Antony-Samy, Karsten Dalsgaard Bjerre, Saara Salmenlinna, Kurt Fuursted, Anette Hansen, Umaer Naseer |
|---|---|
| Přispěvatelé: | Helsinki One Health (HOH), Waterborne pathogens, Food Hygiene and Environmental Health, University of Helsinki |
| Jazyk: | angličtina |
| Rok vydání: | 2022 |
| Předmět: |
CHOLERAE NON-O1
SEPSIS Epidemiology Public Health Environmental and Occupational Health PARAHAEMOLYTICUS WATERS Europe VULNIFICUS INFECTIONS Virology Vibrio Infections 3121 General medicine internal medicine and other clinical medicine Humans Vibrio parahaemolyticus GERMAN Phylogeny Aged Retrospective Studies |
| Zdroj: | Eurosurveillance |
| Popis: | Background Vibriosis cases in Northern European countries and countries bordering the Baltic Sea increased during heatwaves in 2014 and 2018. Aim We describe the epidemiology of vibriosis and the genetic diversity of Vibrio spp. isolates from Norway, Sweden, Denmark, Finland, Poland and Estonia in 2018, a year with an exceptionally warm summer. Methods In a retrospective study, we analysed demographics, geographical distribution, seasonality, causative species and severity of non-travel-related vibriosis cases in 2018. Data sources included surveillance systems, national laboratory notification databases and/or nationwide surveys to public health microbiology laboratories. Moreover, we performed whole genome sequencing and multilocus sequence typing of available isolates from 2014 to 2018 to map their genetic diversity. Results In 2018, we identified 445 non-travel-related vibriosis cases in the study countries, considerably more than the median of 126 cases between 2014 and 2017 (range: 87–272). The main reported mode of transmission was exposure to seawater. We observed a species-specific geographical disparity of vibriosis cases across the Nordic-Baltic region. Severe vibriosis was associated with infections caused by Vibrio vulnificus (adjOR: 17.2; 95% CI: 3.3–90.5) or Vibrio parahaemolyticus (adjOR: 2.1; 95% CI: 1.0–4.5), age ≥ 65 years (65–79 years: adjOR: 3.9; 95% CI: 1.7–8.7; ≥ 80 years: adjOR: 15.5; 95% CI: 4.4–54.3) or acquiring infections during summer (adjOR: 5.1; 95% CI: 2.4–10.9). Although phylogenetic analysis revealed diversity between Vibrio spp. isolates, two V. vulnificus clusters were identified. Conclusion Shared sentinel surveillance for vibriosis during summer may be valuable to monitor this emerging public health issue. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|