Insular cortex volume in established bipolar affective disorder: a preliminary MRI study

Autor:	Stephen J. Wood, Gin S Malhi, Ryoichiro Tanino, Christos Pantelis, Mark Walterfang, Tsutomu Takahashi, Michio Suzuki, Murat Yücel
Rok vydání:	2009
Předmět:	Adult Male medicine.medical_specialty Bipolar I disorder Bipolar Disorder Neuroscience (miscellaneous) Insular cortex behavioral disciplines and activities Young Adult Neuroimaging Internal medicine medicine Humans Radiology Nuclear Medicine and imaging Bipolar disorder Cerebral Cortex Analysis of Variance medicine.diagnostic_test musculoskeletal neural and ocular physiology Magnetic resonance imaging Voxel-based morphometry Middle Aged medicine.disease Magnetic Resonance Imaging Psychiatry and Mental health medicine.anatomical_structure nervous system Cerebral cortex Schizophrenia Case-Control Studies behavior and behavior mechanisms Cardiology Female Psychology Neuroscience psychological phenomena and processes
Zdroj:	Psychiatry research. 182(2)
ISSN:	0165-1781
Popis:	This structural magnetic resonance imaging study investigated insular cortex volume in 26 patients with bipolar I disorder and 24 matched controls. While insular volume did not differ between these groups, exploratory analyses demonstrated that the number of depressive episodes correlated negatively with the anterior insular volume in the patients, suggesting it may have a role in the pathophysiology of bipolar disorder.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c0efef63d4996b8105103897f203ea https://pubmed.ncbi.nlm.nih.gov/20417066 Zobrazit plný text záznamu Full Text from ScienceDirect