Derivation of iPS cell line (ICGi032-A) from a patient affected with fragile X syndrome

Autor: Yu. V. Maksimova, Asia R. Shorina, Dmitry V. Yudkin, Irina V. Grishchenko, Natalya A. Lemskaya, M.M. Gridina, E.M. Shitik, J.M. Minina, Alexander A. Dolskiy
Rok vydání: 2021
Předmět:
Zdroj: Stem Cell Research, Vol 57, Iss, Pp 102615-(2021)
ISSN: 1876-7753
Popis: Trinucleotide repeat expansion diseases such as fragile X syndrome are of great interest to study since the mechanism of its development is still unknown. IPS cell lines are some of the most convenient models for studying. The ICGi032-A iPS cell line was obtained from the peripheral blood mononuclear cells of the patient affected with fragile X syndrome. ICGi032-A iPS cell line have a normal karyotype, expression of pluripotency markers and can differentiate in vitro into the cells of three germ layers.
Databáze: OpenAIRE