Trismus in patients with oropharyngeal cancer: relationship with dose in structures of mastication apparatus
| Autor: | Paul I.M. Schmitz, Peter W.J. Voet, David N. Teguh, Willy de Kruijf, Peter van Rooij, Inge Noever, Henri van der Est, Ben J.M. Heijmen, Peter C. Levendag |
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| Přispěvatelé: | Radiotherapy, Hematology |
| Rok vydání: | 2008 |
| Předmět: |
Adult
Male medicine.medical_treatment Brachytherapy Dentistry Trismus Masseter muscle Cohort Studies stomatognathic system SDG 3 - Good Health and Well-being Surveys and Questionnaires Medicine Humans Mastication Aged Radiotherapy business.industry Masseter Muscle Head and neck cancer Pterygoid Muscles Radiotherapy Dosage Middle Aged medicine.disease Masticatory force Radiation therapy Oropharyngeal Neoplasms Otorhinolaryngology Carcinoma Squamous Cell Quality of Life Female medicine.symptom business |
| Zdroj: | Head & Neck-Journal for the Sciences and Specialties of the Head and Neck, 30(5), 622-630. John Wiley & Sons Inc. |
| ISSN: | 1043-3074 |
| Popis: | Background. Our aim was to assess the correla- tion between the radiation therapy (RT) dose to the mastication apparatus and trismus of oropharyngeal cancer patients. Methods. Eighty-one patients treated with RT were analyzed. The masseter, pterygoid, and temporalis muscles and the coro- noid and condyl were delineated on axial CT slices. The mean dose in these structures was correlated with outcome of quality of life questionnaires. Results. Fifty-six (88%) patients responded; 16% of the patients scored grade 3/4 on the Head & Neck 35 ''opening mouth'' question. A significant correlation was observed between dose in masseter and pterygoid muscles and trismus (p 5 .02). Conclusion. Patients treated with brachytherapy received a lower dose in masticatory muscles. A steep dose-effect relation- ship between mean dose in masseter muscle and pterygoid muscles and the probability of having trismus complaints was observed; with every additional 10 Gy to the pterygoid muscle, an increase of the probability of trismus of 24% was observed. V C 2008 Wiley Periodicals, Inc. Head Neck 30: 622-630, 2008 |
| Databáze: | OpenAIRE |
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