Coexistence of antibodies to tick-borne agents of babesiosis and Lyme borreliosis in patients from Cotia county, State of São Paulo, Brazil
| Autor: | Carlos L Massard, Milena Garcia Abrão, Alessandra Scofield, Cláudio R. Madruga, Adivaldo Henrique da Fonseca, Virginia Lucia Nazario Bonoldi, Natalino Hajime Yoshinari, Cleber O. Soares |
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| Rok vydání: | 2003 |
| Předmět: |
Male
Microbiology (medical) lcsh:Arctic medicine. Tropical medicine lcsh:RC955-962 Blotting Western tick-borne disease lcsh:QR1-502 Antibodies Protozoan Enzyme-Linked Immunosorbent Assay Tick lcsh:Microbiology Ticks Lyme disease parasitic diseases Animals Humans Medicine Borrelia burgdorferi Child Tick-borne disease biology business.industry babesiosis Insect Bites and Stings Babesia bovis Babesiosis borreliosis medicine.disease biology.organism_classification Antibodies Bacterial lyme disease Virology coinfection spirochetosis Immunology Coinfection Erythema migrans Cattle lyme borreliosis business Brazil |
| Zdroj: | Memórias do Instituto Oswaldo Cruz., Vol 98, Iss 3, Pp 311-318 (2003) Memórias do Instituto Oswaldo Cruz, Volume: 98, Issue: 3, Pages: 311-318, Published: APR 2003 |
| ISSN: | 0074-0276 |
| DOI: | 10.1590/s0074-02762003000300004 |
| Popis: | This paper reports a case of coinfection caused by pathogens of Lyme disease and babesiosis in brothers. This was the first case of borreliosis in Brazil, acquired in Cotia County, State of São Paulo, Brazil. Both children had tick bite history, presented erythema migrans, fever, arthralgia, mialgia, and developed positive serology (ELISA and Western-blotting) directed to Borrelia burgdorferi G 39/40 and Babesia bovis antigens, mainly of IgM class antibodies, suggestive of acute disease. Also, high frequencies of antibodies to B. bovis was observed in a group of 59 Brazilian patients with Lyme borreliosis (25.4%), when compared with that obtained in a normal control group (10.2%) (chi-square = 5.6; p < 0.05). Interestingly, both children presented the highest titers for IgM antibodies directed to both infective diseases, among all patients with Lyme borreliosis. |
| Databáze: | OpenAIRE |
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