A Randomized Multicenter Trial Comparing the GlucoWatch Biographer With Standard Glucose Monitoring in Children With Type 1 Diabetes
| Autor: | Chase Hp, T. Wysocki, Nelly Mauras, Roy W. Beck, William V. Tamborlane, Katrina J. Ruedy, Kollman C, Dongyuan Xing, Stuart A. Weinzimer, Eva Tsalikian, Bruce A. Buckingham |
|---|---|
| Rok vydání: | 2005 |
| Předmět: |
Male
Research design Pediatrics medicine.medical_specialty Adolescent Endocrinology Diabetes and Metabolism Hypoglycemia Skin Diseases Patient satisfaction Surveys and Questionnaires Blood Glucose Self-Monitoring Diabetes mellitus Multicenter trial Internal Medicine Humans Medicine Child Monitoring Physiologic Glycemic Glycated Hemoglobin Advanced and Specialized Nursing Type 1 diabetes business.industry medicine.disease Diabetes Mellitus Type 1 Patient Satisfaction Female business |
| Zdroj: | Diabetes Care. 28:1101-1106 |
| ISSN: | 1935-5548 0149-5992 |
| Popis: | OBJECTIVE—This study assesses whether use of the GlucoWatch G2 Biographer (GW2B) in addition to standard glucose monitoring lowers HbA1c and reduces hypoglycemia compared with standard glucose monitoring alone. RESEARCH DESIGN AND METHODS—In all, 200 subjects aged 7 to RESULTS—The mean HbA1c at baseline was 8.0% in both groups; at 6 months, HbA1c was 7.9% in the usual care group and 8.1% in the GW2B group (95% CI for mean reduction in the GW2B group compared with the usual care group −0.4 to 0.1%; P = 0.15). A decrease in HbA1c of ≥0.5% was achieved in 21% of the usual care group and 28% of the GW2B group (P = 0.29). Severe hypoglycemia events occurred in 7% of the GW2B group and in 2% of the usual care group (P = 0.10). In the GW2B group, sensor use declined throughout the study from a mean value of 2.1 times/week in the 1st month to 1.5 times/week in the 6th month. Reasons given for declining use included skin irritation (76%), frequent skips (56%), excessive alarms (47%), and inaccurate readings (33%). CONCLUSIONS—Use of the GW2B in addition to standard glucose monitoring did not improve glycemic control or reduce the frequency of severe hypoglycemia. Skin reactions and other problems led to decreasing sensor use over time. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|