Study on the Organoleptic Intensity Scale for Measuring Oral Malodor
| Autor: | Patricia A Lenton, M. El-Maaytah, G. Majerus, P Spencer, Sushma Nachnani, David Corry, S. Saad, Mel Rosenberg, John R. Duffield, John Greenman |
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| Rok vydání: | 2004 |
| Předmět: |
0301 basic medicine
Organoleptic Trimethylamine Halimeter Methylamines 03 medical and health sciences chemistry.chemical_compound Hemiterpenes 0302 clinical medicine Putrescine Humans Disulfides Hydrogen Sulfide Sulfhydryl Compounds Pentanoic Acids General Dentistry Isovalerate Chromatography Halitosis 030206 dentistry Skatole Intensity (physics) Smell Butyrates 030104 developmental biology chemistry Odor Sensory Thresholds Odorants Linear Models |
| Zdroj: | Journal of Dental Research. 83:81-85 |
| ISSN: | 1544-0591 0022-0345 |
| DOI: | 10.1177/154405910408300116 |
| Popis: | The 0–5 organoleptic scale is used widely in breath research and in trials to measure the efficacy of anti-odor agents. However, the precise relationship between odor scores and gas concentrations of target odorants is unknown. The purpose of this study was to relate mean organoleptic scores from odor judges (n = 7) for pure odorants (n = 8) representative of those found in oral malodor. Judges used a common 0–5 scale to report the odor intensity of sample sets in random order of concentration. Regression analysis of data showed that odor score was proportional to the log concentration of odorant, and comparison of slopes showed H2S to be the most significant in terms of odor power. Detection thresholds (mol.dm−3) were: Skatole (7.2 × 10−13) < methylmercaptan (1.0 × 10−11) < trimethylamine (1.8 × 10−11) < isovalerate (1.8 × 10−11) < butyrate (2.3 × 10−10) < hydrogen sulphide (6.4 × 10−10) < putrescine (9.1 × 10−10) < dimethyl disulphide (5.9 × 10−8). The study demonstrates the exponential nature of the olfactory response and shows that any single compound’s contribution to malodor depends on odor power and threshold in addition to concentration. |
| Databáze: | OpenAIRE |
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