| Autor: |
Huawei Chen, Edwin Clark, Michael Zinda, Michael J. Waring, Stephen E. Fawell, Gordon B. Mills, Paul Lyne, Corinne Reimer, Jonathan R. Dry, Alfred A. Rabow, Tammie C. Yeh, Greg O'Connor, Graeme Walker, Miika J. Ahdesmaki, Larry Bao, Michael Collins, Deborah Lawson, Lillian Castriotta, Shenghua Wen, Jingwen Zhang, Tony Cheung, Scott Boiko, Ian L. Dale, Philip Petteruti, Wenxian Wang, Austin Dulak, Yi Yao, Maureen M. Hattersley, Garrett W. Rhyasen |
| Rok vydání: |
2023 |
| DOI: |
10.1158/1535-7163.22506301 |
| Popis: |
Supplementary Figure 1. AZD5153 shows reduced BRD4 binding activity when BD2 function is abolished; Supplementary Figure 2. AZD5153 modulates MYC protein levels across hematologic cancer cell lines; Supplementary Figure 3. Gene Ontology (GO) analysis of the down-regulated transcripts by AZD5153 across all cell line types; Supplementary Figure 4. IC50 and percent maximal cell kill by AZD5153 and I-BET762 in five hematologic cell lines; Supplementary Figure 5. Tumor growth inhibition across six hematological xenograft Models |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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