Patient activation and patient-reported outcomes of men from a community pharmacy lifestyle intervention after prostate cancer treatment
| Autor: | Bruce A. Griffin, Sara Faithfull, Gary Warner, Karen Poole, Ralph J. F. Manders, Lauren Turner, Kevin Noble, Agnieszka Lemanska, John M Saxton, Zachariah Nazar, John Marshall |
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| Rok vydání: | 2021 |
| Předmět: |
Male
medicine.medical_specialty Urinary system Urinary incontinence Androgen deprivation therapy 03 medical and health sciences Prostate cancer 0302 clinical medicine Quality of life Internal medicine Humans Medicine Patient Reported Outcome Measures 030212 general & internal medicine Life Style Lifestyle interventions Pharmacies Patient Activation Measure business.industry 030503 health policy & services Prostatic Neoplasms Androgen Antagonists medicine.disease Sexual dysfunction Oncology Patient-reported outcomes (PROs) Quality of Life Original Article Patient Participation medicine.symptom Community pharmacy 0305 other medical science Sexual function business |
| Zdroj: | Supportive Care in Cancer |
| ISSN: | 1433-7339 0941-4355 |
| DOI: | 10.1007/s00520-021-06404-5 |
| Popis: | Purpose To report patient activation, which is the knowledge, skills, and confidence in self-managing health conditions, and patient-reported outcomes of men after prostate cancer treatment from a community pharmacy lifestyle intervention. Methods The 3-month lifestyle intervention was delivered to 116 men in nine community pharmacies in the UK. Patient Activation Measure (PAM) was assessed at baseline, 3 and 6 months. Prostate cancer-related function and quality of life were assessed using the European Prostate Cancer Index Composite (EPIC-26) and EuroQOL 5-dimension 5-level (EQ5D-5L) questionnaires at baseline and 6 months. Lifestyle assessments included Mediterranean Diet Adherence Screener (MEDAS) at baseline, 3 and 6 months and Godin Leisure Time Exercise Questionnaire (GLTEQ) at baseline and 3 months. Results PAM score increased from 62 [95% CI 59–65] at baseline to 66 [64–69] after the intervention (p = 0.001) and remained higher at 6 months (p = 0.008). Scores for all the EPIC-26 domains (urinary, bowel and hormonal) were high at both assessments, indicating good function (between 74 [70–78] and 89 [86–91]), except sexual domain, where scores were much lower (21 [17–25] at baseline, increasing to 24 [20–28] at 6 months (p = 0.012)). In EQ5D-5L, 3% of men [1–9] reported self-care problems, while 50% [41–60] reported pain and discomfort, and no significant changes over time. Men who received androgen deprivation therapy, compared with those who did not, reported higher (better) urinary incontinence scores (p p = 0.003), bowel (p p Conclusions The intervention led to significant improvements in patient activation, exercise and diet. Community pharmacy could deliver effective services to address sexual dysfunction, pain and discomfort which are common after prostate cancer. |
| Databáze: | OpenAIRE |
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