Hydrophobic polycationic coatings inactivate wild-type and zanamivir- and/or oseltamivir-resistant human and avian influenza viruses
| Autor: | Jianzhu Chen, Larisa V. Gubareva, Terrence M. Tumpey, Jayanta Haldar, Alexander M. Klibanov |
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| Rok vydání: | 2007 |
| Předmět: |
Oseltamivir
Mutant Bioengineering Biology medicine.disease_cause Antiviral Agents Applied Microbiology and Biotechnology Virus Cell Line Microbiology chemistry.chemical_compound Zanamivir Drug Resistance Viral medicine Animals Humans Polyethyleneimine Enzyme Inhibitors Wild type General Medicine Virology Influenza A virus subtype H5N1 chemistry Influenza A virus biology.protein Viral disease Neuraminidase Biotechnology medicine.drug |
| Zdroj: | Biotechnology Letters. 30:475-479 |
| ISSN: | 1573-6776 0141-5492 |
| Popis: | Glass slides painted with the hydrophobic long-chained polycation N,N-dodecyl,methyl-polyethylenimine (N,N-dodecyl,methyl-PEI) are highly lethal to waterborne influenza A viruses, including not only wild-type human and avian strains but also their neuraminidase mutants resistant to currently used anti-influenza drugs. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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