Lean body mass is better than body surface area in correcting GFR
| Autor: | Hongwei Si, Shengzu Chen, Jianzhong Liu, Zhili Lei, Jianhua Geng, Sijin Li |
|---|---|
| Rok vydání: | 2012 |
| Předmět: |
Body surface area
Adult Male Correlation coefficient business.industry Body Surface Area Significant difference Body Weight General Medicine Hydronephrosis Middle Aged Kidney Function Tests Linear regression Lean body mass Medicine Humans Regression Analysis Radiology Nuclear Medicine and imaging In patient Female business Nuclear medicine Radioisotope Renography Student's t-test Glomerular Filtration Rate |
| Zdroj: | Clinical nuclear medicine. 38(5) |
| ISSN: | 1536-0229 |
| Popis: | PURPOSE The Gates-based renography (gGFR) and plasma-based clearance rate (pGFR) are conventionally corrected with body surface area (BSA). Limited studies indicated that the lean body mass (LBM) might be better than BSA in correcting pGFR. Therefore, we suggest that LBM is also better in correcting gGFR and improve the correlation coefficient between gGFR and pGFR. METHOD During June 2009 and December 2010, the gGFR and pGFR of 63 patients with hydronephrosis were measured and corrected with BSA and LBM, respectively. The correlation and regression analyses were conducted to illustrate the power of BSA and LBM correction. RESULTS In a paired t test, there was no significant difference between pGFR and gGFR in patients with stages 1 and 2, although this was significant in stages 3 and 4. However, neither LBM nor BSA correction could eliminate the difference. In all patients (N = 63), the correlation coefficient (r) between pGFR and gGFR was 0.794 (P |
| Databáze: | OpenAIRE |
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