Hepatitis C seroprevalence in an at-risk population in the southwest Madrid region of Spain
| Autor: | Guadalupe Montes Ramírez, Susana Berbel León, Francisco Javier Sánchez Jiménez, Lourdes Visedo Campillo, Pilar Lasala López, Mercedes Martínez Abad, Elena López Vega, Cristina Murillo, Lourdes García Bermúdez, Noelia Villafranca Ortega, Beatriz Carrascosa Aguilar, María Jesús Izquierdo, Paloma López Hermosa Seseña, Sandra Sánchez Lozano, María Espejo, Isabel Núñez, Sandra Agudo Fernández, Sònia López, Cristina Guisado Pérez, Jesús Zambrano Álvarez, Isabel Mariño Pfeiffer, Conrado M Fernández Rodríguez, Gil Rodriguez Caravaca, Maria Luisa García, Isabel Ayuso Hernández, Antonia García del Val, M. Luisa Castro Pastor |
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| Rok vydání: | 2016 |
| Předmět: |
Adult
Liver Cirrhosis Male medicine.medical_specialty Urban Population Hepatitis C virus Population Comorbidity medicine.disease_cause 03 medical and health sciences Body piercing 0302 clinical medicine Risk-Taking Risk Factors Seroepidemiologic Studies Internal medicine Epidemiology medicine Seroprevalence Humans Mass Screening In patient 030212 general & internal medicine Viremia education At-Risk Population Aged education.field_of_study Primary Health Care business.industry interests Hepatitis C Hepatitis C Antibodies Middle Aged medicine.disease Cross-Sectional Studies Spain Immunology RNA Viral 030211 gastroenterology & hepatology Female business interests.hobby |
| Zdroj: | Gastroenterologia y hepatologia. 39(10) |
| ISSN: | 0210-5705 |
| Popis: | Introduction The estimated seroprevalence of hepatitis C virus (HCV) in Spain is 1.7%, but is much higher in the at-risk population. The most efficient national screening strategy is unclear. Aims To estimate the prevalence of HCV among the at-risk population seen in primary care (PC), and to determine their epidemiological profile. Materials and methods Cross-sectional descriptive prevalence study that included adult patients with risk factors for HCV infection seen in PC in the southwest Madrid region between 2010 and 2012. Results A total of 158 patients (men = 51.3%), mean age 46 years (SD = 16.6), were included. The most common risk factors were hypertransaminasaemia (44.3%) and major surgery (13.3%). Immigration, unsafe sexual practices, and tattoos or body piercing were more prevalent in patients younger than 45 years of age. Fifteen patients (9.5%) were positive for anti-HCV; 9 of these (5.7%) were HCV-ARN positive. Of the positive patients, 4 (44.4%) had significant fibrosis at diagnosis (F3–F4). Male patients had a higher rate of positive anti-HCV results (13.8 vs. 5.3%; p = 0.072), as did patients older than 45 years of age (12.8 vs. 6.3%; p = 0.167). Intravenous and intranasal drug use were associated with a higher rate of positive anti-HCV results (50 vs. 8.5%; p = 0.005 and 66.7 vs. 8.4%; p = 0.001, respectively). Conclusions Patients with risk factors for HCV infection have high seroprevalence. Screening programmes must therefore be implemented to detect HCV infection in this population in PC. |
| Databáze: | OpenAIRE |
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