Speckle‐Tracking Echocardiography in Dogs With Patent Ductus Arteriosus: Effect of Percutaneous Closure on Cardiac Mechanics
| Autor: | Chiara Locatelli, I. Spalla, C. Bussadori, Paola Brambilla, Anna Maria Zanaboni |
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| Rok vydání: | 2016 |
| Předmět: |
Male
congenital hereditary and neonatal diseases and abnormalities medicine.medical_specialty Systole 040301 veterinary sciences Cardiology Diastole Hemodynamics Speckle tracking echocardiography Standard Article 030204 cardiovascular system & hematology Strain 0403 veterinary science Ventricular Dysfunction Left 03 medical and health sciences Dogs 0302 clinical medicine Internal medicine Ductus arteriosus Animals Medicine Dog Diseases Ductus Arteriosus Patent Congenital heart disease Body surface area Ejection fraction Ventricular Remodeling General Veterinary Ductus arteriosus closure business.industry Strain rate 04 agricultural and veterinary sciences Standard Articles medicine.anatomical_structure Echocardiography Female SMALL ANIMAL business |
| Zdroj: | Journal of Veterinary Internal Medicine |
| ISSN: | 1939-1676 0891-6640 |
| Popis: | Background Patent ductus arteriosus (PDA) is 1 of the most common congenital heart defects in dogs and percutaneous closure is effective in achieving ductal closure; PDA closure is associated with abrupt hemodynamic changes. Hypothesis A marked decrease in standard parameters of systolic function as assessed by M- or B-mode echocardiography after PDA closure was identified in previous studies. Speckle tracking echocardiography can provide further insight into the effect of PDA closure on cardiac mechanics in dogs affected by PDA. Animals Twenty-five client-owned dogs with PDA. Methods Prospective study. Dogs were recruited over a 2-year period. Complete echocardiographic evaluation was performed before and 24 hours after PDA closure, including standard (end-diastolic volumes indexed to body surface area in B- and M-mode [EDVIB/M], end-systolic volumes indexed to body surface area in B- and M-mode [ESVIB/M], allometric scaling in diastole [AlloD] and systole [AlloS], pulmonary flow to systemic flow [Qs/Qp], ejection fraction [EF], and fractional shortening [FS]), and advanced speckle-tracking echocardiography (STE): global longitudinal, radial, circumferential and transverse strain (S), and strain rate (SR). Results Patent ductus arteriosus closure was associated with statistically significant decreases in EDVIM/B and ESVIM/B, AlloD and AlloS, SI, EF, and FS. A statistically significant decrease in the absolute values of radial, transverse, and circumferential S and SR was observed, whereas longitudinal S and SR did not change significantly. Conclusion and Clinical Importance Patent ductus arteriosus closure by percutaneous approach is associated with marked decreases of conventional echocardiographic parameters as a result of the changes in loading conditions, but no evidence of systolic dysfunction was identified by means of STE, as none of the S and SR values were below reference ranges. In the short term, contractility is enhanced in the long axis (long S/SR values were not statistically different before and after closure) and decreases to normal values in short axis (circumferential, radial, and transversal S/SR decreased to normal reference range). |
| Databáze: | OpenAIRE |
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