Nontoxigenic Vibrio cholerae Non-O1/O139 Isolate from a Case of Human Gastroenteritis in the U.S. Gulf Coast
| Autor: | Shah M. Rashed, Nur A. Hasan, Nicholas G. Conger, Rita R. Colwell, Talayeh Rezayat, D. Jay Grimes, Kimberly J. Griffitt, Peter J. Blatz, Seon Young Choi, Anwar Huq |
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| Rok vydání: | 2015 |
| Předmět: |
Adult
Male Microbiology (medical) Lineage (genetic) Virulence Factors Virulence Biology medicine.disease_cause Microbiology Vibrio cholerae non-O1 Phylogenetics Vibrio Infections Gene Order medicine Cluster Analysis Humans Gene Phylogeny Phylogenetic tree Chromosome Mapping Computational Biology Bacteriology United States Gastroenteritis Molecular Typing Genes Bacterial Vibrio cholerae Genome Bacterial |
| Zdroj: | Journal of Clinical Microbiology. 53:9-14 |
| ISSN: | 1098-660X 0095-1137 |
| Popis: | An occurrence of Vibrio cholerae non-O1/O139 gastroenteritis in the U.S. Gulf Coast is reported here. Genomic analysis revealed that the isolate lacked known virulence factors associated with the clinical outcome of a V. cholerae infection but did contain putative genomic islands and other accessory virulence factors. Many of these factors are widespread among environmental strains of V. cholerae , suggesting that there might be additional virulence factors in non-O1/O139 V. cholerae yet to be determined. Phylogenetic analysis revealed that the isolate belonged to a phyletic lineage of environmental V. cholerae isolates associated with sporadic cases of gastroenteritis in the Western Hemisphere, suggesting a need to monitor non-O1/O139 V. cholerae in the interest of public health. |
| Databáze: | OpenAIRE |
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