20-hydroxyecdysone and juvenile hormone influence tyrosine hydroxylase activity inDrosophilafemales under normal and heat stress conditions
Autor: | Evgenia K. Karpova, N. E. Gruntenko, I. Y. Rauschenbach, N. A. Chentsova, N. V. Adonyeva |
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Rok vydání: | 2009 |
Předmět: |
medicine.medical_specialty
Tyrosine 3-Monooxygenase Physiology 20-Hydroxyecdysone Biochemistry chemistry.chemical_compound Dopamine Internal medicine medicine Melanogaster Animals Tyrosine hydroxylase biology Wild type General Medicine biology.organism_classification Enzyme assay Juvenile Hormones Ecdysterone Endocrinology chemistry Insect Science Juvenile hormone biology.protein Drosophila Female Heat-Shock Response medicine.drug |
Zdroj: | Archives of Insect Biochemistry and Physiology. 72:263-272 |
ISSN: | 1520-6327 0739-4462 |
DOI: | 10.1002/arch.20337 |
Popis: | The effects of exogenous 20-hydroxyecdysone (20E) and the juvenile hormone (JH) on the activity of the tyrosine hydroxylase (TH), the first and rate-limiting DA biosynthetic enzyme, has been studied in young females of wild type D. virilis and D. melanogaster under normal conditions and under heat stress (38 degrees C). Both 20E feeding of the flies and JH application led to a substantial rise in TH activity. A rise in JH and 20E levels was found not to prevent the response of TH to heat stress, but to change the intensity of its response to the stress exposure. Putative mechanisms of regulation of DA level by 20E and JH in Drosophila females are discussed. |
Databáze: | OpenAIRE |
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