Comparison of survival outcomes of alcohol-related hepatocellular carcinoma with or without liver cirrhosis; a ten-year experience
| Autor: | Myoung Hun Chae, Chang Hwi Yoon, Young-Joo Jin, Jinwoo Lee, Jung Hwan Yu, Jongbeom Shin |
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| Rok vydání: | 2019 |
| Předmět: |
Adult
Liver Cirrhosis Male medicine.medical_specialty Cirrhosis Multivariate analysis Carcinoma Hepatocellular Time Factors Alcohol-Related Hepatocellular Carcinoma viruses overall survival Observational Study Gastroenterology 03 medical and health sciences child-turcotte pugh class 0302 clinical medicine Internal medicine Carcinoma Medicine Humans heterocyclic compounds 030212 general & internal medicine Liver Diseases Alcoholic Aged Retrospective Studies Aged 80 and over Tumor size business.industry Medical record cirrhosis Liver Neoplasms Retrospective cohort study non-cirrhosis General Medicine hepatocellular carcinoma Middle Aged medicine.disease enzymes and coenzymes (carbohydrates) 030220 oncology & carcinogenesis Hepatocellular carcinoma ComputingMethodologies_DOCUMENTANDTEXTPROCESSING Female business Research Article |
| Zdroj: | Medicine |
| ISSN: | 1536-5964 |
| Popis: | Supplemental Digital Content is available in the text We evaluated overall survivals (OSs) of alcohol-related hepatocellular carcinoma (HCC) patients without LC compared to those with LC. Between 2005 and 2015, 1343 patients were initially diagnosed as having HCC in our hospital. Of these, 186 alcohol-related HCC patients were enrolled in this study, and their medical records were retrospectively analyzed. Significant alcohol intake was defined as more than 210 grams/week for men and more than 140 grams/week for women. Non-cirrhotic HCC was observed in 37.1% of the 186 patients. Cumulative OS rates were significantly higher in non-cirrhotic patients (P = .006). For the 117 cirrhotic patients, cumulative OS rate was significantly higher in the CTP class A patients than in the CTP class B (P |
| Databáze: | OpenAIRE |
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