Probenecid (Benemid) intoxication with status epilepticus

Autor: Thomas V. Inglesby, Vincent J. Rizzuto, William J. Grace
Rok vydání: 1965
Předmět:
Zdroj: The American Journal of Medicine. 38:646-648
ISSN: 0002-9343
DOI: 10.1016/0002-9343(65)90140-3
Popis: A forty-nine year old man who attempted suicide by taking 47 gm. of probenecid and who recovered subsequently is described. There has been no previous documentation of probenecid overdosage in man, although various toxic effects with average doses have occasionally been reported. The clinical manifestations included coma and status epilepticus. The serum urate fell to very low levels. No significant alterations in the metabolism of calcium or phosphorus could be demonstrated.
Databáze: OpenAIRE