Conventional ultrasound integrated with elastosonography and B-flow imaging in the diagnosis of thyroid nodular lesions
| Autor: | Giuseppina Napolitano, Salvatore Cappabianca, Luca Brunese, Graziella Di Grezia, Ettore Squillaci, Alfonso Reginelli, Fabrizio Urraro, Nicola Maggialetti |
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| Přispěvatelé: | Reginelli, Alfonso, Urraro, Fabrizio, di Grezia, Graziella, Napolitano, Giuseppina, Maggialetti, Nicola, Cappabianca, Salvatore, Brunese, Luca, Squillaci, Ettore |
| Jazyk: | angličtina |
| Rok vydání: | 2014 |
| Předmět: |
Male
Risk of malignancy Nodule Predictive Value of Test Adenocarcinoma Follicular Medicine Prospective Studies Thyroid Nodule Lymph nodes Thyroid Neoplasm Thyroid Medicine (all) Ultrasound General Medicine Middle Aged medicine.anatomical_structure Thyroid Cancer Papillary Elasticity Imaging Techniques Lymph node Female Radiology medicine.symptom Elastosonography Human Thyroid nodules Adult medicine.medical_specialty Adolescent Biopsy Fine-Needle Thyroid nodular Conventional ultrasound Sensitivity and Specificity Young Adult Settore MED/36 - Diagnostica per Immagini e Radioterapia Elasticity Imaging Technique Predictive Value of Tests Humans Thyroid Neoplasms Ultrasonography Interventional Aged Suspicious for Malignancy business.industry Carcinoma Nodule (medicine) medicine.disease Carcinoma Papillary Prospective Studie BFI Surgery business Nuclear medicine Thyroid Nodule Elastosonography BFI Lymph nodes |
| Popis: | The purpose of this study was to evaluate the sonographic features of thyroid nodules suspicious for malignancy with standard examination in B-mode and Color Doppler associated with modern techniques such as ultrasound RTE (Real Time Elastosonography) and BFI (B-flow imaging) in correlation with the results of the sonographically guided fine-needle aspiration to establish their role in predicting the risk of malignancy.Between November 2012 and January 2014, 354 consecutive patients (age range, 18–73 years; mean age ± SD, 41.2 ± 9.2 years; 90 male and 264 female) with 493 suspected nodules (maximum diameter > 9 mm) were enrolled in this prospective study.Sonographic, elastosonographic and BFI examinations were performed with a commercially available real-time ultrasound system, and all patients also underwent a cytologic evaluation. Patients with suspicious or malignant cytologic features underwent surgery.On histologic examination, 71 of 493 nodules were malignant (62 papillary thyroid carcinoma, 1 Hürthle cell carcinoma, and 8 follicular carcinoma). All sonographic characteristics, which were potential predictors of thyroid malignancy (microcalcifications, hypoechogenicity, absence of a halo, and a predominantly solid composition), were found in different percentages in both histologically verified malignant and benign nodules. For BFI, pattern 3 (≥4 signs and distance > 2 mm) was the most predictive factor for malignancy (specificity, 99.6%; sensitivity, 65.2%), whereas pattern 2 (≥4 signs and distance |
| Databáze: | OpenAIRE |
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