Diagnostic Value of Rapid Biophysical Profile in Comparison to Biophysical Profile in Pregnant Women with Insulin-dependent Diabetes
| Autor: | Mobin Naqshbandi, Nasrin Soufizadeh, Karim Sharifi, Sima Aslani, Saghar Tamri, Sara Behafarid, Fariba Farhadifar |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Biophysical profile
medicine.medical_specialty Embryo Health Prenatal care lcsh:Gynecology and obstetrics 03 medical and health sciences symbols.namesake 0302 clinical medicine Medicine 030212 general & internal medicine lcsh:RG1-991 030219 obstetrics & reproductive medicine Receiver operating characteristic Biophysical Profile business.industry Obstetrics Pearson's chi-squared test Obstetrics and Gynecology Gestational age Predictive value Rapid Biophysical Profile Reproductive Medicine Insulin dependent diabetes Insulin-dependent Diabetes symbols Original Article Pregnant Women Family Practice business Area under the roc curve |
| Zdroj: | Journal of Family & Reproductive Health Journal of Family and Reproductive Health, Vol 13, Iss 4 (2020) |
| ISSN: | 1735-9392 1735-8949 |
| DOI: | 10.18502/jfrh.v13i4.2648 |
| Popis: | Objective: Having a rapid and low cost diagnostic approach in assessment of fetal wellbeing is an important goal for prenatal care process. The aim of this study was to determine the diagnostic value of rapid biophysical profile (rBPP) in comparison to biophysical profile (BPP). Materials and methods: In this study 142 pregnant women with insulin-dependent diabetes referred to Besat Hospital (Sanandaj, Iran) were evaluated in terms of fetal health. Age, gestational age and non-stress test (NST) data of patients were collected. The fetuses were evaluated using the standard BPP and selected rBPP methods. Sensitivity, specificity, positive predictive values (PPV) and negative predictive values (NPV) were calculated. The receiver operating characteristic (ROC) curve was plotted. The data were analyzed in Stata 14 software, using appropriate statistical analyses. Results: The mean ± standard deviation (SD) of maternal age and gestational age of the studied subjects were 30.6 ± 6.3 and 35.6 ± 1.5 weeks, respectively. The frequency of normal cases were 126 (88.7%) in the BPP method and 121 (85.2%) in the rBPP method. The results showed that sensitivity, specificity, PPV and NPV of rBPP in this study were 56.2%, 90.5%, 42.8% and 94.2%, respectively. The area under the ROC curve was 73.3%. Pearson Test showed a significant correlation between scores obtained through BPP and rBPP methods (p < 0.001). Conclusion: Considering the high profile of the sensitivity and PPV of the RBPP method compared to BPP, rBPP method has a better capacity to discriminate non-distressed fetuses from distress-exposed fetuses. It can also be used as a quick and easy method in crowded centers with limited evaluation tests, where not much skill is needed. |
| Databáze: | OpenAIRE |
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