Gender differences in the modifiable risk factors associated with the presence of prediabetes: A systematic review

Autor: Saadia Ghafoor, Sabariah Noor Harun, Siti Maisharah Sheikh Ghadzi, Sania Siddiqui, Hadzliana Zainal
Rok vydání: 2020
Předmět:
Zdroj: Diabetes & Metabolic Syndrome: Clinical Research & Reviews. 14:1243-1252
ISSN: 1871-4021
Popis: Background Prediabetes is a risk state for the future development of type 2 diabetes. Previously, it was evident that the risk factors for diabetes differ by gender. However, conclusive evidence regarding the gender difference in modifiable risk factors associated with the presence of pre-diabetes is still lacking. Aims To systematically identify and summarize the available literature on whether the modifiable risk factors associated with prediabetes displays similar relationship in both the genders. Methods A systematic search was performed on electronic databases i.e. PubMed, EBSCOhost, and Scopus using “sex”, “gender”, “modifiable risk factors” and “prediabetes” as keywords. Reference list from identified studies was used to augment the search strategy. Methodological quality and results from individual studies were summarized in tables. Results Gender differences in the risk factor association were observed among reviewed studies. Overall, reported association between risk factors and prediabetes apparently stronger among men. In particular, abdominal obesity, dyslipidemia, smoking and alcohol drinking habits were risk factors that showed prominent association among men. Hypertension and poor diet quality may appear to be stronger among women. General obesity showed stringent hold, while physical activity not significantly associated with the risk of prediabetes in both the genders. Conclusions Evidence suggests the existence of gender differences in risk factors associated with prediabetes, demands future researchers to analyze data separately based on gender. The consideration and the implementation of gender differences in health policies and in diabetes prevention programs may improve the quality of care and reduce number of diabetes prevalence among prediabetic subjects.
Databáze: OpenAIRE