Seasonal variation in 25-hydroxyvitamin D and parathyroid hormone concentrations in healthy elderly people
| Autor: | Peter R. Woodhouse, V. Hegarty, Kay-Tee Khaw |
|---|---|
| Rok vydání: | 1994 |
| Předmět: |
Male
medicine.medical_specialty Aging Population Parathyroid hormone Reference Values Internal medicine medicine Vitamin D and neurology Humans Vitamin D education Geriatric Assessment Aged education.field_of_study business.industry General Medicine Healthy elderly Seasonality medicine.disease United Kingdom Endocrinology Parathyroid Hormone Calcium Female Seasons Geriatrics and Gerontology business |
| Zdroj: | Age and ageing. 23(6) |
| ISSN: | 0002-0729 |
| Popis: | Seasonal variation in serum 25-hydroxyvitamin D and parathyroid hormone concentration was examined longitudinally in 96 community-dwelling men and women aged 65-74 years. Mean 25-hydroxyvitamin D concentration was lowest in winter (22.7 mmol/l) and highest in summer (35.4 mmol/l); mean parathyroid hormone concentration was highest in winter (3.55 pmol/l) and lowest in summer (3.24 pmol/l): these seasonal variations were highly significant (p < 0.0001). Parathyroid hormone concentrations were inversely related to 25-hydroxyvitamin D concentrations (p < 0.0001). Seasonal variation of 25-hydroxyvitamin D and parathyroid hormone concentration is marked in older healthy adults in Britain. Even in summer, mean 25-hydroxyvitamin D concentrations are low; maintaining more optimal vitamin D levels in the general population may have clinical and public health benefits. |
| Databáze: | OpenAIRE |
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