Cognitive aids for people with early stage dementia versus treatment as usual (Dementia Early Stage Cognitive Aids New Trial (DESCANT)): study protocol for a randomised controlled trial

Autor: Helen Chester, Paul Clarkson, Linda Davies, Jane Hughes, Muhammad Saiful Islam, Narinder Kapur, Martin Orrell, Julie Peconi, Rosa Pitts, Fiona Poland, Ian Russell, David Challis, Members of the HoSt-D (Home Support in Dementia) Programme Management Group
Jazyk: angličtina
Rok vydání: 2018
Předmět:
Gerontology
Quality of life
Activities of daily living
Time Factors
Cost effectiveness
Medicine (miscellaneous)
Effectiveness
Pilot Projects
Community
Process evaluation
law.invention
03 medical and health sciences
Study Protocol
0302 clinical medicine
Cognition
Randomized controlled trial
law
Psychosocial outcomes
Memory
Activities of Daily Living
Adaptation
Psychological
Pragmatic Clinical Trials as Topic
medicine
Dementia
Humans
Multicenter Studies as Topic
Pharmacology (medical)
030212 general & internal medicine
Memory aids
health care economics and organizations
lcsh:R5-920
Research ethics
business.industry
Bristol Activities of Daily Living Scale
medicine.disease
Mental health
United Kingdom
Treatment Outcome
Pragmatic randomised trial
Feasibility Studies
Cost-effectiveness
Early-stage dementia
lcsh:Medicine (General)
business
Early-stage dementia
Memory aids
Community
Psychosocial outcomes
Quality of life
Effectiveness
Cost-effectiveness
Pragmatic randomised trial
Process evaluation
030217 neurology & neurosurgery
Zdroj: Trials
Chester, H, Clarkson, P, Davies, L, Hughes, J, Islam, M S, Kapur, N, Orrell, M, Peconi, J, Pitts, R, Poland, F, Russell, I, Challis, D & HoSt-D (Home Support in Dementia) Programme Management Group 2018, ' Cognitive aids for people with early stage dementia versus treatment as usual (Dementia Early Stage Cognitive Aids New Trial [DESCANT]): study protocol for a randomised controlled trial ', Trials, vol. 19, no. 546, pp. 546 . https://doi.org/10.1186/s13063-018-2933-8
Trials, Vol 19, Iss 1, Pp 1-11 (2018)
DOI: 10.1186/s13063-018-2933-8
Popis: Background There is a growing need for an evidence-based approach to home support for people with dementia and their carers following diagnosis but research on the effectiveness and cost-effectiveness of different approaches is sparse. The Dementia Early Stage Cognitive Aids New Trial (DESCANT) will evaluate the clinical and cost-effectiveness of a range of memory aids, training and support to people with mild to moderate dementia and their carers at home and compares that intervention with treatment as usual. Methods/design This is a multi-site, pragmatic randomised trial preceded by a feasibility study and internal pilot. We aim to allocate at random 360 pairs comprising a person with mild to moderate dementia and an identified carer between the DESCANT intervention and treatment as usual. We assess participants at baseline, 13 and 26 weeks. The primary outcome measure is the Bristol Activities of Daily Living Scale; other participant outcomes include cognition, quality of life, activities of daily living and social networking; carer outcomes include quality of life, sense of competence and mental health. To enhance this quantitative evaluation we are conducting a qualitative component and a process evaluation to assess the implementation process and identify contextual factors associated with variation. Discussion The DESCANT intervention reflects current policy to enhance the capabilities of people with dementia after diagnosis and their carers. If it is clinically and cost-effective, its modest nature and cost will enhance the likelihood of it being incorporated into mainstream practice. Trial registration Current Controlled Trials, ISRCTN12591717. Registered on 29 July 2016. Protocol number: 31288: North West - Haydock Research Ethics Committee, 20/06/2016, ref.: 16/NW/0389.
Databáze: OpenAIRE
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