Establishing a novel 3D printing bioinks system with recombinant human collagen

Autor:	Zixun, Wang, Yang, Yang, Yunbo, Gao, Zhaoxian, Xu, Shulin, Yang, Mingjie, Jin
Rok vydání:	2022
Předmět:	Tissue Engineering Tissue Scaffolds Structural Biology Printing Three-Dimensional Spectroscopy Fourier Transform Infrared Human Umbilical Vein Endothelial Cells Humans Collagen General Medicine Molecular Biology Biochemistry
Zdroj:	International Journal of Biological Macromolecules. 211:400-409
ISSN:	0141-8130
Popis:	Bioinks are one of the key elements in realizing three-dimensional (3D) bioprinting. However, bioinks prepared from conventional collagen are hindered to their further applications due to concerns of collagen purity, unstable mechanical properties, and low solubility under neutralized conditions. This study aimed to develop a reliable UV-curable bioink system from a novel water-soluble recombinant human collagen (RHC). RHC was modified by methacrylic anhydride (MAA) and later crosslinked by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC)/N-hydroxysuccinimide (NHS) to obtain Pro-RHCMA.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::506485a13cf73b035bb2cf4fa98fa8f5 https://doi.org/10.1016/j.ijbiomac.2022.05.088 Zobrazit plný text záznamu Full Text from ScienceDirect