Autor: |
Zixun, Wang, Yang, Yang, Yunbo, Gao, Zhaoxian, Xu, Shulin, Yang, Mingjie, Jin |
Rok vydání: |
2022 |
Předmět: |
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Zdroj: |
International Journal of Biological Macromolecules. 211:400-409 |
ISSN: |
0141-8130 |
Popis: |
Bioinks are one of the key elements in realizing three-dimensional (3D) bioprinting. However, bioinks prepared from conventional collagen are hindered to their further applications due to concerns of collagen purity, unstable mechanical properties, and low solubility under neutralized conditions. This study aimed to develop a reliable UV-curable bioink system from a novel water-soluble recombinant human collagen (RHC). RHC was modified by methacrylic anhydride (MAA) and later crosslinked by 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide hydrochloride (EDC)/N-hydroxysuccinimide (NHS) to obtain Pro-RHCMA. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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