Allopurinol hypersensitivity syndrome as a cause of hepatic fibrin-ring granulomas
| Autor: | M. Vanderstigel, Portos Jl, Elie Serge Zafrani, A. Schaeffer, J.L. Lejonc |
|---|---|
| Rok vydání: | 1986 |
| Předmět: |
Adult
Male Pathology medicine.medical_specialty Allopurinol Allopurinol hypersensitivity syndrome Q fever Drug Hypersensitivity hemic and lymphatic diseases Humans Medicine Eosinophilia Fibrin Granuloma Hepatology business.industry Liver Diseases Hepatobiliary disease Gastroenterology medicine.disease Rash Liver Abnormal Liver Function Test Chemical and Drug Induced Liver Injury medicine.symptom business medicine.drug |
| Zdroj: | Gastroenterology. 90:188-190 |
| ISSN: | 0016-5085 |
| DOI: | 10.1016/0016-5085(86)90092-2 |
| Popis: | Hepatic fibrin-ring granulomas were found in a 35-yr-old man who developed fever, myalgias, rash, eosinophilia, and abnormal liver function tests 4 wk after the beginning of allopurinol treatment. All clinical and biochemical abnormalities spontaneously resolved within 6 wk after cessation of therapy. There was no evidence for Q fever or Hodgkin's disease, which are the recognized causes of hepatic fibrin-ring granulomas. It is suggested that allopurinol hypersensitivity might be an additional cause of these peculiar granulomas. |
| Databáze: | OpenAIRE |
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