The pharmacist’s role in chimeric antigen receptor T cell therapy
Autor: | Julie Kennerly-Shah, Jennifer P Booth, Carolyn L Kusoski |
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Rok vydání: | 2020 |
Předmět: |
medicine.medical_specialty
T cell Pharmacist Pharmacy Staff education 030204 cardiovascular system & hematology Pharmacists Immunotherapy Adoptive 03 medical and health sciences Professional Role 0302 clinical medicine Neoplasms medicine Humans Pharmacology (medical) Intensive care medicine Receptors Chimeric Antigen business.industry Cancer medicine.disease Chimeric antigen receptor Clinical pharmacy medicine.anatomical_structure Oncology Pharmaceutical Services 030220 oncology & carcinogenesis Chimeric Antigen Receptor T-Cell Therapy business |
Zdroj: | Journal of Oncology Pharmacy Practice. 26:1725-1731 |
ISSN: | 1477-092X 1078-1552 |
DOI: | 10.1177/1078155220948940 |
Popis: | The emergence and efficacy of chimeric antigen receptor (CAR) T cell therapy in previously incurable malignancies represents a promising paradigm shift in cancer care. However, it is not without significant clinical, operational, and financial considerations. Pharmacists should be prepared to fulfill the various roles in CAR T cell therapy provision including: policy development; electronic medical record build; patient and staff education; patient selection; procurement, storage, and handling; medication administration and supportive care; management of adverse reactions; and quality tracking. Our commentary provides an overview of the opportunities for pharmacy involvement in the implementation and maintenance of a CAR T cell therapy program with an emphasis on the importance of pharmacy involvement as part of a multidisciplinary approach to care. Although some institutions have dedicated a CAR T cell pharmacist to meet the demands of emerging CAR T cell therapy, we believe that clinical pharmacists practicing in hematopoietic stem cell transplant and hematology/oncology have the skills and training to fulfill the pharmacist’s role in CAR T cell therapy. |
Databáze: | OpenAIRE |
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