Short Overview of ROS as Cell Function Regulators and Their Implications in Therapy Concepts
| Autor: | Ana Čipak Gašparović, Pierre-Alexis Mouthuy, Lidija Milkovic, Marina Cindric, Neven Zarkovic |
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| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
ROS formation
Cellular functions Cell Communication Review Biology Regenerative Medicine reactive oxygen species (ROS) cellular processes medicine.disease_cause Neoplasms medicine Humans cancer redox signaling lcsh:QH301-705.5 chemistry.chemical_classification therapy Reactive oxygen species Basic Medical Sciences General Medicine Cell function physiology metabolism lcsh:Biology (General) chemistry Reactive Oxygen Species Oxidation-Reduction Neuroscience Oxidative stress Signal Transduction |
| Zdroj: | Cells Cells, Vol 8, Iss 8, p 793 (2019) |
| Popis: | The importance of reactive oxygen species (ROS) has been gradually acknowledged over the last four decades. Initially perceived as unwanted products of detrimental oxidative stress, they have been upgraded since, and now ROS are also known to be essential for the regulation of physiological cellular functions through redox signaling. In the majority of cases, metabolic demands, along with other stimuli, are vital for ROS formation and their actions. In this review, we focus on the role of ROS in regulating cell functioning and communication among themselves. The relevance of ROS in therapy concepts is also addressed here. |
| Databáze: | OpenAIRE |
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