Does Age Matter? Estimating Risks of Locoregional Recurrence After Breast-conservative Surgery
| Autor: | Rosaria Meucci, Agostino Chiaravalloti, Marco Materazzo, Paolo Orsaria, Gianluca Vanni, Ljuba Morando, Jonathan Caspi, Marco Pellicciaro, Lucia Anemona, Rosaria Barbarino, Chiara Adriana Pistolese, Oreste Claudio Buonomo, Ilaria Portarena, Camilla Deiana, Maria Rolando D'Angelillo, Tommaso Perretta |
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| Rok vydání: | 2020 |
| Předmět: |
Risk
Cancer Research medicine.medical_specialty Breast Neoplasms Subgroup analysis Mastectomy Segmental General Biochemistry Genetics and Molecular Biology 03 medical and health sciences 0302 clinical medicine Breast cancer Biomarkers Tumor medicine Humans Operation time In patient Aged Retrospective Studies Aged 80 and over Postoperative Care Pharmacology business.industry Incidence (epidemiology) Middle Aged Prognosis Tailored treatment medicine.disease Surgery Breast conservative surgery Receptors Estrogen Case-Control Studies 030220 oncology & carcinogenesis Ki67 index Female Neoplasm Recurrence Local business Research Article |
| Zdroj: | In Vivo |
| ISSN: | 1791-7549 0258-851X |
| Popis: | Background/Aim: In 2016, in the United States, more than 50% of breast cancer (BC) cases were diagnosed in patients older than 60 years of age. Our study aimed to estimate the risk of locoregional recurrence (LR) in patients who underwent breast-conservative treatment (BCT), according to age. Patients and Methods: This retrospective monocentric study analyzed 613 cases of patients who underwent BCT between 2003 and 2014. Patients were divided into groups according to age: Under70 (under 70 years old) and Over70 (above 70 years old). Margins width, histology results, prognostic and predictive factors were compared. Subgroup analysis was performed for patients who experienced LR. Results: LR Incidence among Under70 and Over70 was 5.4% and 1.7%, respectively (p |
| Databáze: | OpenAIRE |
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