Statin use and risk of nonmelanoma skin cancer: a nationwide study in Denmark
| Autor: | Anton Pottegård, Søren Friis, David Gaist, S Arnspang, Klaus Ejner Andersen, Jesper Hallas, Ole Clemmensen |
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| Rok vydání: | 2014 |
| Předmět: |
nonmelanoma
Male Risk Adult Oncology Cancer Research medicine.medical_specialty Skin Neoplasms Statin medicine.drug_class Short Communication Denmark Population Hydroxymethylglutaryl-CoA Reductase Inhibitors/administration & dosage statins Internal medicine medicine Humans skin and connective tissue diseases education neoplasms Aged Aged 80 and over education.field_of_study skin cancer integumentary system business.industry fungi Confounding Case-control study Odds ratio Squamous cell skin cancer Middle Aged Statin treatment medicine.disease Denmark/epidemiology Surgery stomatognathic diseases Case-Control Studies epidemiology Skin Neoplasms/epidemiology Female Hydroxymethylglutaryl-CoA Reductase Inhibitors Skin cancer business |
| Zdroj: | Pedersen, S A, Pottegård, A, Friis, S, Clemmensen, O, Andersen, K E, Hallas, J, Gaist, D & Andersen, K E 2015, ' Statin use and risk of nonmelanoma skin cancer : a nationwide study in Denmark ', British Journal of Cancer, vol. 112, no. 1, pp. 153-156 . https://doi.org/10.1038/bjc.2014.527 British Journal of Cancer |
| ISSN: | 1532-1827 0007-0920 |
| DOI: | 10.1038/bjc.2014.527 |
| Popis: | Background: Evidence is conflicting regarding statin use and risk of basal cell (BCC) and squamous cell skin cancer (SCC). Methods: Using Danish nationwide registries, we identified all patients with incident BCC/SCC during 2005-2009 and matched them to population controls. We computed odds ratios (ORs) for BCC and SCC associated with statin use. Results: We identified 38 484 cases of BCC and 3724 cases of SCC. Statin ever use was associated with ORs of 1.09 (CI: 1.06-1.13) for BCC and 1.01 (CI: 0.91-1.11) for SCC. Conclusions: Statin use was not associated with risk of SCC. Residual confounding plausibly explains the marginally increased risk of BCC. |
| Databáze: | OpenAIRE |
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