Long‐term effects of spasticity treatment, including selective dorsal rhizotomy, for individuals with cerebral palsy

Autor: Michael H. Schwartz, Mark L. McMulkin, Tom F. Novacheck, Elizabeth A. Duffy, Bruce A. MacWilliams, Brian Po-Jung Chen, Meghan E. Munger
Rok vydání: 2021
Předmět:
Zdroj: Developmental Medicine & Child Neurology. 64:561-568
ISSN: 1469-8749
0012-1622
DOI: 10.1111/dmcn.15075
Popis: AIM To understand the long-term effects of comprehensive spasticity treatment, including selective dorsal rhizotomy (SDR), on individuals with spastic cerebral palsy. METHOD This was a pre-registered, multicenter, retrospectively matched cohort study. Children were matched on age range and spasticity at baseline. Children at one center underwent spasticity treatment including SDR (Yes-SDR, n=35) and antispastic injections. Children at two other centers had no SDR (No-SDR, n=40 total) and limited antispastic injections. All underwent subsequent orthopedic treatment. Participants returned for comprehensive long-term assessment (age ≥21y, follow-up ≥10y). Assessment included spasticity, contracture, bony alignment, strength, gait, walking energy, function, pain, stiffness, participation, and quality of life. RESULTS Spasticity was effectively reduced at long-term assessment in the Yes-SDR group and was unchanged in the No-SDR group. There were no meaningful differences between the groups in any measure except the Gait Deviation Index (Yes-SDR + 11 vs No-SDR + 5) and walking speed (Yes-SDR unchanged, No-SDR declined 25%). The Yes-SDR group underwent more subsequent orthopedic surgery (11.9 vs 9.7 per individual) and antispastic injections to the lower limbs (14.4 vs
Databáze: OpenAIRE
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