Incidental finding of prostate cancer in Transurethral Resection of Prostate (TURP) specimens: a retrospective analysis from a Tertiary Care Hospital in Pakistan
| Autor: | Naveen Faridi, Muhammad Ali Yousuf, Muhammad Irfan, Aziz Abdullah, Taimoor Khalid Janjua, Shahbaz Mustafa Memon, Muhammad Talha Iqbal |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Adult
Male medicine.medical_specialty medicine.medical_treatment Prostatic Hyperplasia urologic and male genital diseases Tertiary Care Centers Prostate cancer Prostate Internal medicine Carcinoma medicine Retrospective analysis Humans Pakistan Stage (cooking) Transurethral resection of the prostate Aged Retrospective Studies Aged 80 and over Incidental Findings business.industry Incidence (epidemiology) Incidence Research Transurethral Resection of Prostate Cancer Prostatic Neoplasms General Medicine Middle Aged medicine.disease Incidental prostate cancer TURP specimens medicine.anatomical_structure Neoplasm Grading business |
| Zdroj: | The Pan African Medical Journal Pan African Medical Journal; Vol. 39 No. 1 (2021) |
| ISSN: | 1937-8688 |
| Popis: | Introduction:incidental prostate cancer findings reflect the great burden of prostatic cancer across the globe. Our 10 year retrospective analysis aimed to identify the incidence and clinic-pathologic features of prostate cancer incidentally detected in patients undergoing transurethral resection of the prostate (TURP) for benign prostatic hyperplasia (BPH), and to estimate the clinical value of pathologic review of all TURP specimens. Methods:after excluding patients with a known diagnosis of prostate cancer prior to TURP a total of 2,386 men (ages 25-98) were identified by pathology (TURP) specimens. Yearly incidences, Gleason score, grade, pathologic stage were recorded for all incidental prostate cancer patients. Results:a total of 256 (10.7%) patients were found to have prostate cancer. Mean Age was 68.51±9.22 years. T1a and T1b stage prostatic carcinoma was found in 9.9% and 90.1% of these patients respectively. Forty-nine (49%) patients had higher Gleason scores (>7). After subtracting average incidences between 5-year intervals, a statistical rise of almost 4% was found. Conclusion:our analysis concludes that a large proportion (10.7%) of patients had incidental prostate cancer and the incidence was increasing in recent years in Pakistan and in comparison, to Asian countries. In Pakistan there is a scarcity of updated national cancer registries. The growing incidence of high Gleason scores requires keen and prompt attention. The diverse ethnic and socioeconomic background of patients propels their propensity towards loss of follow up with already limited tertiary healthcare institutes in Pakistan. This pathologic review of TURP specimens is valuable for Asiatic and non-Asiatic populations. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|