Malignidad en pacientes con sarcoidosis
| Autor: | Senol Kobak, Mehmet Orman, Hüseyin Semiz, Fidan Yildiz |
|---|---|
| Přispěvatelé: | Ege Üniversitesi, İstinye Üniversitesi, Tıp Fakültesi, Dahili Tıp Bilimleri Bölümü, Şenol Kobak / 0000-0001-8270-640X, Kobak, Şenol, Şenol Kobak / 12782228700 |
| Rok vydání: | 2021 |
| Předmět: |
medicine.medical_specialty
hydroxychloroquine Hodgkin disease Sarcoidosis retrospective study dipeptidyl carboxypeptidase testis cancer Malignancy Article Breast cancer breast cancer Rheumatology lofgren syndrome male middle aged medicine thyroid cancer follow up case report controlled study human Prospective cohort study Thyroid cancer Testicular cancer clinical article business.industry Incidence (epidemiology) Incidence adult disease association General Medicine medicine.disease cohort analysis Dermatology Malignidad aged female arthritis protein blood level Cohort histopathology uveitis disease duration business Incidencia |
| Zdroj: | Reumatología Clínica (English Edition). 17:49-51 |
| ISSN: | 2173-5743 |
| DOI: | 10.1016/j.reumae.2019.04.002 |
| Popis: | PubMed Yılı: 2019 The relationship between sarcoidosis and malignancy is not clear yet. We retrospectively evaluated 131 sarcoidosis patients followed-up at the single Rheumatology center. The incidence of malignancies was investigated in this cohort. A total of 6 (4.6%) patients with malignancy were identified in our cohort of 131 patients with sarcoidosis. Hodgkin lymphoma (HL) was detected in three patients, followed by one patient with breast cancer, one patient with thyroid cancer and one patient with testicular cancer. All patients had chronic sarcoidosis with pulmonary involvement, and only 1 patient had acute sarcoidosis with Löfgren's syndrome. HL developed concomitantly with sarcoidosis in one patient while other two patients developed disease before and after sarcoidosis diagnosis. Two patients with solid tumors developed malignancy years before sarcoidosis diagnosis, while one patient developed thyroid cancer during sarcoidosis follow-up. All 6 sarcoidosis–malignancy patients survived after six year years follow up. We found low incidence of malignancy in patients with sarcoidosis in our small cohort. The sarcoidosis–malignancy relationship can only be a coincidence and/or can be explained by a common pathogenesis. New prospective studies involving large patients series are needed in this regard. © 2019 Elsevier España, S.L.U. and Sociedad Española de Reumatología y Colegio Mexicano de Reumatología WOS:000608393600010 31153889 |
| Databáze: | OpenAIRE |
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