Microembolic Air Load During Contrast-Transcranial Doppler: A Trigger for Migraine With Aura?
| Autor: | Chiara Falcone, Gennaro Bussone, Domenico D'Amico, Susanna Usai, Luigi Caputi, Gian Paolo Anzola, Maria Rita Carriero, Licia Grazzi, Eugenio Parati, Massimo Del Sette |
|---|---|
| Rok vydání: | 2010 |
| Předmět: |
Adult
Male Adolescent Ultrasonography Doppler Transcranial medicine.medical_treatment Migraine with Aura Foramen Ovale Patent Comorbidity Young Adult Statistical significance Valsalva maneuver Embolism Air Humans Medicine Prospective cohort study Aged Microbubbles business.industry Middle Aged medicine.disease Migraine with aura Transcranial Doppler Neurology Anesthesia Cortical spreading depression Patent foramen ovale Female Neurology (clinical) medicine.symptom business |
| Zdroj: | Headache: The Journal of Head and Face Pain. 50:1320-1327 |
| ISSN: | 0017-8748 |
| Popis: | (Headache 2010;50:1320-1327) Background.— There is a well-known association between migraine with aura (MA) and right-to-left shunt (RILES) because of patent foramen ovale (PFO). The occurrence of MA attacks after microbubble (MB) injection during contrast-enhanced transcranial Doppler (ce-TCD) has been recently described. Objectives.— The aim of this study was to analyze the prevalence of RILES in a consecutive cohort of MA patients and to characterize the occurrence of MA attacks after diagnostic ce-TCD. Methods.— A total of 159 consecutive MA patients underwent ce-TCD with air-mixed saline to disclose RILES. RILES was characterized in terms of MB amount (small-moderate or large) and occurrence at rest and/or during Valsalva maneuver (permanent or latent). Results.— RILES was revealed in 79/159 patients (∼50%). Permanent RILES were detected in 56/79 (71%) and latent RILES in 23/79 (29%) MA patients. The occurrence of a typical MA attack was overall observed in 12/159 patients (7.5%; 95% CI: 4-12.8%), but arose only in RILES-positive ones, immediately after ce-TCD (12/79; 15.2%; P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text