Relationship between myocardial fibrosis and epicardial and surface electrocardiogram Q waves in man
| Autor: | Richard H. Helfant, Vidya S. Banka, Homayoon Pasdar, Monty M. Bodenheimer, Robert G. Trout, George A. Hermann |
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| Rok vydání: | 1979 |
| Předmět: |
medicine.medical_specialty
Muscle loss business.industry Myocardium Coronary Disease Heart Anatomy Angina Pectoris Surface electrocardiogram QRS complex Surface ecg Electrocardiography Internal medicine Cardiology Medicine Humans Myocardial fibrosis cardiovascular diseases Coronary Artery Bypass Cardiology and Cardiovascular Medicine business |
| Zdroj: | Journal of electrocardiology. 12(2) |
| ISSN: | 0022-0736 |
| Popis: | Summary The extent of transmural loss of myocardium in man which results in both the development and duration of Q waves on local electrocardiograms (ECGs) and the surface ECG is incompletely understood. Accordingly, at the time of open heart surgery, epicardial electrograms and transmural biopsies from the same site were obtained in 18 patients (19 sites). Of nine areas with epicardial R waves, eight were histologically normal while one had only Biopsies obtained from twelve areas were reflected by a normal QRS on the corresponding leads of the surface ECG. Eight biopsies were normal while three demonstrated less than 50% involvement. Only one had more than 50% transmural muscle loss in the zone corresponding to the ECG localization. Of seven biopsies obtained from areas with associated pathologic surface ECG Q waves, five had greater than 50% transmural loss. Thus, a quantitative relationship appears to exist between the amount and location of myocardial fibrosis and both the presence and duration of Q waves on epicardial electrograms. This relationship also appears to hold to a somewhat lesser degree with Q waves exhibited on the surface ECG. |
| Databáze: | OpenAIRE |
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