Psychological trauma and functional somatic syndromes: a systematic review and meta-analysis

Autor: Sandra M. Ahumada, Jessica Gundy Cuneo, Lisa Johnson Wright, Veronica Reis, Niloofar Afari, Golnaz Golnari, Sheeva Mostoufi
Rok vydání: 2014
Předmět:
medicine.medical_specialty
Physical Injury - Accidents and Adverse Effects
Medical and Health Sciences
Article
Stress Disorders
Post-Traumatic

Irritable Bowel Syndrome
functional somatic syndromes
2.3 Psychological
Fibromyalgia
Behavioral and Social Science
medicine
Chronic fatigue syndrome
Humans
Aetiology
Psychiatry
Applied Psychology
Irritable bowel syndrome
Stress Disorders
business.industry
Temporomandibular disorder
Pain Research
Disputed aetiology and other
Psychology and Cognitive Sciences
Chronic pain
PTSD
Neuromuscular Diseases
Temporomandibular Joint Disorders
medicine.disease
Post-Traumatic Stress Disorder (PTSD)
Anxiety Disorders
meta-analysis
Psychiatry and Mental health
Posttraumatic stress
trauma
Mental Health
Good Health and Well Being
Meta-analysis
Post-Traumatic
Chronic Pain
social and economic factors
business
Mind and Body
Psychological trauma
Zdroj: Psychosomatic medicine, vol 76, iss 1
Popis: ObjectiveThis meta-analysis systematically examined the association of reported psychological trauma and posttraumatic stress disorder (PTSD) with functional somatic syndromes including fibromyalgia, chronic widespread pain, chronic fatigue syndrome, temporomandibular disorder, and irritable bowel syndrome. Our goals were to determine the overall effect size of the association and to examine moderators of the relationship.MethodsLiterature searches identified 71 studies with a control or comparison group and examined the association of the syndromes with traumatic events including abuse of a psychological, emotional, sexual, or physical nature sustained during childhood or adulthood, combat exposure, or PTSD. A random-effects model was used to estimate the pooled odds ratio and 95% confidence interval. Planned subgroup analyses and meta-regression examined potential moderators.ResultsIndividuals who reported exposure to trauma were 2.7 (95% confidence interval = 2.27-3.10) times more likely to have a functional somatic syndrome. This association was robust against both publication bias and the generally low quality of the literature. The magnitude of the association with PTSD was significantly larger than that with sexual or physical abuse. The association of reported trauma with chronic fatigue syndrome was larger than the association with either irritable bowel syndrome or fibromyalgia. Studies using nonvalidated questionnaires or self-report of trauma reported larger associations than did those using validated questionnaires.ConclusionsFindings are consistent with the hypothesis that traumatic events are associated with an increased prevalence of functional somatic syndromes. The analyses also highlight limitations of the existing literature and emphasize the importance of prospective studies, examining the potential similarities and differences of these conditions, and pursuing hypothesis-driven studies of the mechanisms underlying the link between trauma, PTSD, and functional somatic syndromes.
Databáze: OpenAIRE