Sildenafil Citrate: Novel Therapy in the Management of Ovarian Torsion
| Autor: | Priyanka H. Vora, Umesh V Athavale, Kedar N. Ganla, Rana A. Choudhary |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
0301 basic medicine
endocrine system medicine.medical_specialty antioxidant Necrosis endocrine system diseases Sildenafil medicine.medical_treatment Case Report Ovary sildenafil citrate lcsh:Gynecology and obstetrics 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Edema medicine lcsh:RG1-991 030219 obstetrics & reproductive medicine In vitro fertilisation business.industry Ovarian torsion reperfusion injury medicine.disease female genital diseases and pregnancy complications Surgery 030104 developmental biology medicine.anatomical_structure Reproductive Medicine chemistry ovarian torsion medicine.symptom detorsion business edema Reperfusion injury Perfusion |
| Zdroj: | Journal of Human Reproductive Sciences, Vol 12, Iss 4, Pp 351-354 (2019) Journal of Human Reproductive Sciences |
| ISSN: | 0974-1208 |
| Popis: | Ovarian torsion is defined as partial or complete rotation of ovarian vascular pedicle, leading to the obstruction of venous outflow and arterial inflow. It is an emergency condition with an incidence of 2%–15% in patients with adnexal masses. The main risk in ovarian torsion is an ovarian mass or an enlarged ovary with a long pedicle. Due to the rotation of ovarian tissue axis on its vascular pedicle, there is compression of vessels followed by stromal edema, hemorrhagic infarction, and necrosis of adnexa. Expedient diagnosis poses a difficult challenge because clinical presentation is a variable and often misleading. We report a case of right ovarian torsion after oocyte retrieval for in vitro fertilization, where vaginal sildenafil citrate was successfully used to reduce ovarian edema by improving venous drainage. It also helped in maintaining ovarian tissue perfusion and preventing reperfusion injury and spontaneous detorsion of the ovary without any surgical intervention. |
| Databáze: | OpenAIRE |
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