Use of a Monoclonal Antibody againstBabesia bovisMerozoite Surface Antigen-2c for the Development of a Competitive ELISA Test
| Autor: | Patricia Ines Zamorano, Anabel Rodriguez, Mariana Dominguez, Marisa Diana Farber, Silvina Elizabeth Wilkowsky, Susana Torioni de Echaide, Gustavo Asenzo, Osvaldo Zabal, Carlos E. Suarez, Monica Florin-Christensen, Ignacio Echaide |
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| Rok vydání: | 2004 |
| Předmět: |
medicine.drug_class
Protozoan Proteins Cattle Diseases Antigens Protozoan Enzyme-Linked Immunosorbent Assay Monoclonal antibody General Biochemistry Genetics and Molecular Biology law.invention History and Philosophy of Science Antigen law Babesiosis medicine Animals biology General Neuroscience Antibodies Monoclonal Membrane Proteins Babesia bovis biology.organism_classification medicine.disease Virology Monoclonal Recombinant DNA biology.protein Cattle Antibody |
| Zdroj: | Annals of the New York Academy of Sciences. 1026:165-170 |
| ISSN: | 1749-6632 0077-8923 |
| Popis: | Bovine babesiosis caused by Babesia bovis is a disease that hampers the production of beef and dairy cattle in tropical and subtropical regions of the world. New diagnostic methods based on recombinant antigens constitute valuable biotechnological tools for the strategic control of this disease. We have developed a competitive enzyme-linked immunosorbent assay that includes a recombinant form of the merozoite surface antigen-2c and a novel monoclonal antibody against it. Preliminary results showed that this test is able to identify specific antibodies against B. bovis from experimentally and naturally infected cattle. |
| Databáze: | OpenAIRE |
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