Factors influencing the outcome of deep infection following total knee arthroplasty
| Autor: | Naoki Nakano, Ryosuke Kuroda, Tomoyuki Matsumoto, Hirotsugu Muratsu, Masahiro Kurosaka, Takafumi Hiranaka, Nobuhiro Tsumura, Kazunari Ishida |
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| Rok vydání: | 2015 |
| Předmět: |
musculoskeletal diseases
Knee function Male medicine.medical_specialty Prosthesis-Related Infections medicine.medical_treatment Total knee arthroplasty Logistic regression Prosthesis Risk Assessment Japan Risk Factors medicine Humans Orthopedics and Sports Medicine Arthroplasty Replacement Knee Aged Retrospective Studies business.industry Incidence Evidence-based medicine Odds ratio Osteoarthritis Knee musculoskeletal system Arthroplasty Surgery Multicenter study Female business Knee Prosthesis Follow-Up Studies |
| Zdroj: | The Knee. 22(4) |
| ISSN: | 1873-5800 |
| Popis: | Background Whereas clinical studies have revealed a number of important risk factors for postoperative infection following total knee arthroplasty (TKA), it is unclear which factor influences clinical results. A multicenter study was therefore performed by reviewing 51 patients with deep infection after TKA and seeking for the factors related to clinical outcomes. Methods Fifty-one deep infections after TKA were treated from 2000 to 2011 at the multicenter including a university or three arthroplasty centers. Among them, two clinical outcome measures including retention of prosthesis at initial treatment and functional prosthetic knee were assessed for several factors such as age, sex, primary diagnosis, onset time after primary TKA, type of hospital where the primary TKA was performed and the organism's resistance to methicillin using the logistic regression analysis model. Results Among the factors, type of hospital where the primary TKA was performed and onset time after primary TKA had higher multivariable-adjusted odds ratios (ORs) for retention of primary prosthesis (ORs 35.21 and 11.69, respectively.). The cases which primary surgery were performed in arthroplasty centers had higher multivariable-adjusted ORs for functional prosthetic knee (OR 4.9). Thirty-one infection cases with non-methicillin-resistant organisms were all able to keep functional prosthetic knee after the operation, whereas 13 out of 20 infection cases with methicillin-resistant organisms lost their knee function after the operation. Conclusions Onset time after primary TKA, type of hospital where the primary surgery was performed and the organism's resistance to methicillin are important factors influencing the clinical outcomes after infected TKA. Level of Evidence Level 3. Retrospective comparative study. |
| Databáze: | OpenAIRE |
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