Qualitative and quantitative assessment of posterior segment optical coherence tomography images using standard photos: the Liwan Eye Study
| Autor: | Sean K. Wang, Yanxian Chen, Xinxing Guo, Mingguang He, Wenyong Huang, Ou Xiao, Ran Liu |
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| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
Male
medicine.medical_specialty Visual acuity genetic structures Intraclass correlation Concordance Eye disease Visual Acuity Retinal Pigment Epithelium posterior segment 030207 dermatology & venereal diseases 03 medical and health sciences qualitative grading 0302 clinical medicine Optical coherence tomography Retinal Diseases Ophthalmology Medical imaging Medicine Humans Aged optical coherence tomography quantitative measurement medicine.diagnostic_test business.industry Research General Medicine Macular degeneration Middle Aged medicine.disease eye diseases Posterior segment of eyeball 030221 ophthalmology & optometry Female sense organs medicine.symptom business Tomography Optical Coherence |
| Zdroj: | BMJ Open |
| ISSN: | 2044-6055 |
| Popis: | Background/aimsTo develop a standardised grading scheme, using standard photos, for spectral-domain ocular coherence tomography (SD-OCT) images of the posterior eye and evaluate the interobserver agreement among trained ophthalmologists in identifying pathological changes.MethodsSubjects were recruited from Liwan District, Guangzhou, with SD-OCT data collection from June 2013 to November 2013 as part of 10-year follow-up visits from the Liwan Eye Study. All subjects underwent SD-OCT imaging of the macula with scanning lines analysed by two ophthalmologists to assess for the presence of 12 different posterior segment lesions. Per cent agreement for each lesion between the graders and quantitative measures of dome-shaped macula (DSM) height and choroidal thickness were calculated.ResultsA total of 679 SD-OCT images from 679 subjects were independently evaluated by the two graders. Each of the 12 lesions was successfully graded as present or absent in over 96% of images. For all lesions, per cent agreement between observers was over 90%, ranging from 90.7% for epiretinal membranes and retinal pigment epithelium thickenings to 99.7% for full thickness macular holes and retinal detachments. Quantitative measurements of DSM height and choroidal thickness at three locations of the eye all exhibited intraclass correlation scores between the two graders of greater than 0.9.ConclusionOur study demonstrates high concordance between graders in characterising posterior segment lesions using SD-OCT images, validating the continued use of this imaging modality in the diagnosis of posterior eye disease. |
| Databáze: | OpenAIRE |
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