Systemic sclerosis with normal or nonspecific nailfold capillaroscopy
| Autor: | Jean-Pierre Gaitz, Fanny Fichel, Nathalie Baudot, Camille Francès, Salim Trad, Patricia Senet, Coralie Barbe |
|---|---|
| Rok vydání: | 2013 |
| Předmět: |
Adult
Male medicine.medical_specialty Nailfold videocapillaroscopy Dermatology Severity of Illness Index Microscopic Angioscopy Medicine Humans Telangiectasis skin and connective tissue diseases Nailfold Capillaroscopy Aged Retrospective Studies Microscopy Video Scleroderma Systemic integumentary system business.industry Microangiopathy Raynaud Disease Middle Aged medicine.disease Respiratory Function Tests Nails Antibodies Antinuclear Microvessels Female business |
| Zdroj: | Dermatology (Basel, Switzerland). 228(4) |
| ISSN: | 1421-9832 |
| Popis: | Background: In systemic sclerosis (SSc), a specific nailfold videocapillaroscopy (NVC) pattern is observed in 90% of cases and seems to be associated with severity and progression of the disease. Objective: To describe the characteristics of SSc patients with normal or nonspecific (normal/nonspecific) NVC. Methods: In a retrospective cohort study, clinical features and visceral involvements of 25 SSc cases with normal/nonspecific NVC were compared to 63 SSc controls with the SSc-specific NVC pattern. Results: Normal/nonspecific NVC versus SSc-specific NVC pattern was significantly associated with absence of skin sclerosis (32 vs. 6.3%, p = 0.004), absence of telangiectasia (47.8 vs. 17.3%, p = 0.006) and absence of sclerodactyly (60 vs. 25.4%, p = 0.002), and less frequent severe pulmonary involvement (26.3 vs. 58.2%, p = 0.017). Conclusion: Normal/nonspecific NVC in SSc patients appears to be associated with less severe skin involvement and less frequent severe pulmonary involvement. |
| Databáze: | OpenAIRE |
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