Basal cell carcinoma of the prostate: clinicopathologic analysis of three cases and a review of the literature
| Autor: | Yun Yi Kong, Shi Lin Zhang, Jian Nong Wu, Dingwei Ye, Kun Chang, Yao Zhu, Yuan-Yuan Qu, Wei Qiang Yao, Hai Liang Zhang, Bo Dai, Xu Dong Yao |
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| Rok vydání: | 2013 |
| Předmět: |
Male
Pathology medicine.medical_specialty Lung Neoplasms medicine.medical_treatment Bone Neoplasms Case Report Immunoenzyme Techniques Prostate Surgical oncology medicine Biomarkers Tumor Humans Basal cell carcinoma Transurethral resection of the prostate Aged Retrospective Studies medicine.diagnostic_test business.industry Urinary retention Immunochemistry Liver Neoplasms Transurethral Resection of Prostate Prostatic Neoplasms Rectal examination Middle Aged medicine.disease Prognosis Combined Modality Therapy Review Literature as Topic medicine.anatomical_structure Oncology Carcinoma Basal Cell Adenocarcinoma Immunohistochemistry Surgery medicine.symptom business |
| Zdroj: | World Journal of Surgical Oncology |
| ISSN: | 1477-7819 |
| Popis: | Background Although conventional adenocarcinoma accounts for the majority of prostatic carcinomas, it is important to recognize rare variants, like basal cell carcinoma (BCC), which has distinctive histopathological and biological features. Case report We analyzed three cases of prostatic BCC and all of them complained of acute urinary retention and digital rectal examination disclosed a stony hard prostate. However, all of them presented with low prostate-specific antigen. The diagnosis relied on transrectal ultrasound-guided needle biopsies or transurethral resection of the prostate (TURP). The microscopic findings suggested basaloid cells with large pleomorphic nuclei and scant cytoplasm, showing peripheral palisading and forming solid nests, and immunohistochemical markers like 34βE12, p63 and Ki67 staining, were positive. After active treatment, two of the patients are alive with tumor and one died five months after discharge from our hospital. |
| Databáze: | OpenAIRE |
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