Impact of successive exertional heat injuries on thermoregulatory and systemic inflammatory responses in mice
| Autor: | Michelle A. King, Aaron R. Caldwell, Shauna M. Ward, Mark L. Plamper, Lisa R. Leon, Thomas A. Mayer, Jermaine A. Ward, Kentaro Oki |
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| Rok vydání: | 2021 |
| Předmět: |
Hyperthermia
Male Hot Temperature Physiology business.industry Inflammatory response Inflammation medicine.disease Heat Stress Disorders Body Temperature Running Organ damage Mice Inbred C57BL Mice Physiology (medical) Heat shock protein Immunology Medicine Animals medicine.symptom business Body Temperature Regulation |
| Zdroj: | Journal of applied physiology (Bethesda, Md. : 1985). 131(5) |
| ISSN: | 1522-1601 |
| Popis: | Mice undergoing repeated exertional heat injuries, within 1 wk of an initial heat injury, appear to have some protective adaptations. During the second exertional heat injury, mice were able to run longer and sustain higher body temperatures before collapse. Despite this, the mice undergoing a second exertional heat injury were more resilient to the heat as evidenced by attenuated minimum body temperature, higher HPS70 (serum and liver), lower corticosterone, and lower FABP2. |
| Databáze: | OpenAIRE |
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