Detecting Breast Cancer with a Dual-Modality Device
| Autor: | Roland V. Baasch, Christopher L. Vaughan, Lydia Cairncross, Kamila Padia, Tania S. Douglas |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2017 |
| Předmět: |
medicine.medical_specialty
Digital mammography Clinical Biochemistry Article Imaging phantom dense breasts 030218 nuclear medicine & medical imaging 03 medical and health sciences breast cancer 0302 clinical medicine Breast cancer Healthy volunteers medicine Mammography Breast ultrasound oncology_oncogenics lcsh:R5-920 medicine.diagnostic_test business.industry Gold standard (test) medicine.disease 3. Good health Clinical trial full-field digital mammography (FFDM) dual-modality imaging 030220 oncology & carcinogenesis Dual modality Radiology lcsh:Medicine (General) business automated breast ultrasound (ABUS) |
| Zdroj: | Diagnostics; Volume 7; Issue 1; Pages: 17 Diagnostics, Vol 7, Iss 1, p 17 (2017) Diagnostics |
| ISSN: | 2075-4418 |
| DOI: | 10.3390/diagnostics7010017 |
| Popis: | Although mammography has been the gold standard for the early detection of breast cancer, if a woman has dense breast tissue, a false negative diagnosis may occur. Breast ultrasound, whether hand-held or automated, is a useful adjunct to mammography but adds extra time and cost. The primary aim was to demonstrate that our second-generation Aceso system, which combines full-field digital mammography (FFDM) and automated breast ultrasound (ABUS) in a single platform, is able to produce improved quality images that provide clinically meaningful results. Aceso was first tested using two industry standards: a Contrast Detail Mammography (CDMAM) phantom to assess the FFDM images, and the CIRS 054GS phantom to evaluate the ABUS images. In addition, 25 women participated in a clinical trial: 14 were healthy volunteers, while 11 were patients referred by the breast clinic at Groote Schuur Hospital. The CDMAM phantom results showed the FFDM results were better than the European Reference (EUREF) standard of "acceptable" and were approaching "achievable". The ABUS results showed a lateral and axial spatial resolution of 0.5 mm and an adequate depth penetration of 80 mm. Our second-generation Aceso system, with its improved quality of clinical FFDM and ABUS images, has demonstrated its potential for the early detection of breast cancer in a busy clinic. |
| Databáze: | OpenAIRE |
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