Pretreatment pathologic prognostic factors in head and neck squamous cell carcinoma
| Autor: | Alessandra Rinaldo, Brian C. Hunter, Alfio Ferlito, Kenneth O. Devaney |
|---|---|
| Rok vydání: | 1997 |
| Předmět: |
Male
medicine.medical_specialty Pathology Biopsy Physical examination Polymerase Chain Reaction 03 medical and health sciences Cytogenetics 0302 clinical medicine medicine Humans 030223 otorhinolaryngology Head and neck Laryngeal Neoplasms Neoplasm Staging medicine.diagnostic_test business.industry Nucleotide Mapping General Medicine DNA Neoplasm Cell cycle Middle Aged medicine.disease Prognosis Head and neck squamous-cell carcinoma Blotting Southern Otorhinolaryngology Epidermoid carcinoma 030220 oncology & carcinogenesis Carcinoma Squamous Cell business |
| Zdroj: | The Annals of otology, rhinology, and laryngology. 106(11) |
| ISSN: | 0003-4894 |
| Popis: | Squamous carcinomas of the head and neck region are a common problem for the otolaryngologist; surgeons are obliged to draw together disparate lines of evidence — from physical examination, pathology, and radiology — to plan optimal therapy for their patients. This article explores some of the ways in which pathologic analysis of a biopsy specimen in the past (determination of extent of invasion and degree of differentiation), present (including an analysis of the pattern of infiltration and the tumor's DNA content), and, perhaps, the future (possibilities including cytogenetics and analysis of discrete steps in the cell cycle) plays a role in this process. |
| Databáze: | OpenAIRE |
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