Duration of immunity for an inactivated Mycoplasma hyorhinis vaccine in pigs
| Autor: | Kenneth Barrett, Whitney Zoghby, Jeremy Kroll, Lawrence Bryson, Brian Thomas Martinson |
|---|---|
| Rok vydání: | 2019 |
| Předmět: |
Male
Mycoplasma hyorhinis Swine Physiology Arthritis Biology Placebo Microbiology 03 medical and health sciences Pericarditis Immunity medicine Animals Mycoplasma Infections Lung 030304 developmental biology Swine Diseases 0303 health sciences General Veterinary 030306 microbiology Vaccination General Medicine medicine.disease biology.organism_classification Vaccines Inactivated Lameness Bacterial Vaccines Female Polyarthritis |
| Zdroj: | Veterinary Microbiology. 230:273-277 |
| ISSN: | 0378-1135 |
| DOI: | 10.1016/j.vetmic.2019.02.021 |
| Popis: | Mycoplasma hyorhinis (Mhr) is a pathogen of pigs causing polyserositis and polyarthritis. The most susceptible population are nursery pigs of approximately 7 weeks of age, although we have shown that clinical signs can persist into finishing aged animals after a late-nursery infection. We have previously demonstrated the efficacy of a novel inactivated Mhr vaccine for the reduction of lameness and polyserositis in caesarian-derived colostrum-deprived (CDCD) pigs vaccinated at 3 weeks and challenged with Mhr at 6 weeks of age. Here we evaluated the duration of immunity (DOI) of the same vaccine. Vaccine or placebo was administered to CDCD pigs at 3 weeks of age. Pigs were challenged with Mhr at either 10 weeks of age (=7 week DOI) or 13 weeks of age (=10 week DOI). In the 7 week DOI, vaccination provided significant reductions in lameness (p = 0.0018), arthritis (p = 0.0002), and pericarditis (p = 0.0312) versus the placebo control. In the 10 week DOI, a significant reduction in arthritis (p = 0.0320) was observed in the vaccine group as compared to the placebo group. Both vaccine groups showed a significant increase (p |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full Text from ScienceDirect