Cerium Dioxide-Mediated Signal 'On-Off' by Resonance Energy Transfer on a Lab-On-Paper Device for Ultrasensitive Detection of Lead Ions
| Autor: | Lina Zhang, Hao Li, Shenguang Ge, Huang Yuzhen, Li Li, Jinghua Yu, Yan Zhang |
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| Rok vydání: | 2017 |
| Předmět: |
Working electrode
Materials science Inorganic chemistry Deoxyribozyme chemistry.chemical_element Substrate (chemistry) 02 engineering and technology 010402 general chemistry 021001 nanoscience & nanotechnology 01 natural sciences 0104 chemical sciences Catalysis Luminol Matrix (chemical analysis) chemistry.chemical_compound Cerium chemistry Electrochemiluminescence General Materials Science 0210 nano-technology |
| Zdroj: | ACS applied materialsinterfaces. 9(38) |
| ISSN: | 1944-8252 |
| Popis: | In this report, a 3D microfluidic lab-on-paper device for ultrasensitive detection of lead cation was designed using phoenix tree fruit-shaped CeO2 nanoparticles (PFCeO2 NPs) as the catalyst and 50 nm silver NPs (Ag NPs) as the quencher. First, snowflake-like Ag NPs were grown on the paper working electrode through an in situ growth method and used as a matrix for DNAzymes that were specific for lead ions (Pb2+). After the addition of Ag NP-labeled substrate strands, the Ag NPs restrained the electrochemiluminescence (ECL) intensity of luminol greatly through the resonance energy transfer from luminol to Ag NPs. However, under the existence of Pb2+, the substrate strands were separated, and then PFCeO2 NP-labeled signal strands were hybridized with the DNAzymes. The ECL signal was improved greatly under the fast catalytic reaction between PFCeO2 NPs and H2O2, which converted the response from signal off to signal on state, resulting in sensitive detection of Pb2+. Under the optimal conditions, the ECL sig... |
| Databáze: | OpenAIRE |
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