Bodyweight Measures and Lifestyle Habits in Individuals with Multiple Sclerosis and Moderate to Severe Disability

Autor:	Moran Livne-Margolin, Gil Harari, Anat Achiron, Orit Pinhas-Hamiel, Itay Tokatly Latzer
Rok vydání:	2021
Předmět:	medicine.medical_specialty obesity Waist Overweight multiple sclerosis Article 03 medical and health sciences 0302 clinical medicine immune system diseases Internal medicine medicine overweight Medical history 030212 general & internal medicine Prospective cohort study Expanded Disability Status Scale central obesity business.industry Multiple sclerosis expanded disability status scale General Medicine medicine.disease Obesity nervous system diseases Medicine medicine.symptom business Body mass index 030217 neurology & neurosurgery
Zdroj:	Journal of Clinical Medicine Journal of Clinical Medicine; Volume 10; Issue 10; Pages: 2083 Journal of Clinical Medicine, Vol 10, Iss 2083, p 2083 (2021)
ISSN:	2077-0383
Popis:	Multiple sclerosis (MS) is a chronic disease marked by progressive disability and decreased mobility over time. We studied whether individuals with MS of higher disability levels will be more overweight/obese as a result of their immobility and/or recurrent steroid treatments. In a prospective study, 130 individuals with MS and significant disability were classified according to the Expanded Disability Status Scale (EDSS) score as belonging to four groups: EDSS 3.0–4.0 (n = 31, 24%), EDSS 4.5–5.5 (n = 24, 18%), EDSS = 6.0 (n = 44, 34%) and EDSS ≥ 6.5 (n = 31, 24%). Medical history, body mass index (BMI), waist circumference and the level of engagement in physical activity were obtained. The mean ± standard error age was 55.8 ± 0.5 years, disease duration 18.2 ± 1.0 years and EDSS score 5.5 ± 0.1. Disease duration, the number of steroid courses per disease duration, weight, BMI and physical activity did not differ according to the four disability groups. The mean waist circumference increased significantly with increased severity of EDSS, p = 0.03. Increased disability in individuals with MS was not correlated with disease duration, lifestyle habits or overweight/obesity. However, increased disability was associated with central obesity.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ff4cbf50dbb6326081341beb5828ab1 https://pubmed.ncbi.nlm.nih.gov/34066209 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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