Identification of a Key Prenyltransferase Involved in Biosynthesis of the Most Abundant Fungal Meroterpenoids Derived from 3,5-Dimethylorsellinic Acid
| Autor: | Yutaka Ebizuka, Isao Fujii, Ikuro Abe, Tetsuo Kushiro, Takayuki Itoh, Edayileveettil K. Radhakrishnan, Kinya Tokunaga |
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| Rok vydání: | 2012 |
| Předmět: |
Addition reaction
Terpenes Chemistry Stereochemistry Organic Chemistry Prenyltransferase Fungi Aromaticity Resorcinols Dimethylallyltranstransferase Biochemistry Fungal Proteins Terpene Structure-Activity Relationship chemistry.chemical_compound Prenylation Biosynthesis Molecular Medicine Molecular Biology |
| Zdroj: | ChemBioChem. 13:1132-1135 |
| ISSN: | 1439-4227 |
| DOI: | 10.1002/cbic.201200124 |
| Popis: | Destroying aromaticity: A novel prenyltransferase (Trt2) involved in fungal meroterpenoid biosynthesis was shown to catalyze an unusual aromatic addition reaction onto a fully substituted aromatic ring. The prenylated product serves as a key intermediate in the biosynthesis of the most abundant series of meroterpenoids in fungi. |
| Databáze: | OpenAIRE |
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